ncRNA name | Per2 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat Müller cell line rMC-1 |
Methods | siRNA transfection, qRT-PCR, Western blot, immunohistochemistry, immunofluorescence |
Expression pattern | associated |
Functional description | We observe that siRNA silencing of Bmal and Per2 downregulates Kcnj10 expression, suggesting the direct impact of the clock on Kir4.1 channels. |
PubMed ID | 28460049 |
Year | 2017 |
Title | Tumor Necrosis Factor Alpha (TNF-α) Disrupts Kir4.1 Channel Expression Resulting in Müller Cell Dysfunction in the Retina. |
Drug-related ncRNA | NO |
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